BDBM629485 US20230339981, Example 173

SMILES F[C@H]1CN2CCC[C@@]2(COc2nc3N4C[C@H]5CC[C@H](N5)[C@H]4C[C@@H](F)c4nc(c(F)c(n2)c34)-c2cccc3ccc(F)c(C#C)c23)C1

InChI Key InChIKey=YOACFHCCTCIAME-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 629485   

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandPNGBDBM629485(US20230339981, Example 173)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
Go to US Patent