BDBM629451 US20230339981, Example 139

SMILES Oc1cc(-c2nc3CC[C@@H]4[C@@H]5CC[C@H](CN4c4nc(OC[C@@]67CCCN6CC(C7)OC(F)(F)F)nc(c2F)c34)N5)c2c(C#C)c(F)ccc2c1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 629451   

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandPNGBDBM629451(US20230339981, Example 139)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
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