BDBM629427 US20230339981, Example 115

SMILES CC(OC[C@@H]1CC[C@]2(COc3nc4N5C[C@H]6CC[C@H](N6)[C@H]5CCCc5nc(c(F)c(n3)c45)-c3cccc4ccc(F)c(C#C)c34)CCCN12)(C(F)(F)F)C(F)(F)F

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 629427   

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandPNGBDBM629427(US20230339981, Example 115)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
Go to US Patent