BDBM629277 2-(4-fluorophenyl)-N-(4-{7-[methyl(1-methylpiperidin-4-yl)amino]-3-(pyridin-2-yl)-1H-pyrrolo[3,2-b]pyridin-2-yl}pyridin-2-yl)acetamide::US20230339939, Example 39

SMILES CN(C1CCN(C)CC1)c1ccnc2c(c([nH]c12)-c1ccnc(NC(=O)Cc2ccc(F)cc2)c1)-c1ccccn1

InChI Key InChIKey=AZBIOIRZHDKQJI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 629277   

TargetCasein kinase I isoform alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM629277(2-(4-fluorophenyl)-N-(4-{7-[methyl(1-methylpiperid...)
Affinity DataIC50: 3.49nMAssay Description:Recombinant fusion protein of N-terminal Glutathion-S-Transferase (GST) and full-length human CSNK1A1, expressed by baculovirus infected insect cells...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
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TargetCasein kinase I isoform delta(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM629277(2-(4-fluorophenyl)-N-(4-{7-[methyl(1-methylpiperid...)
Affinity DataIC50: 13.6nMAssay Description:Recombinant fusion protein of N-terminal Glutathion-S-Transferase (GST) and full-length human CSNK1D, expressed by baculovirus infected insect cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
Go to US Patent

TargetCasein kinase I isoform alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM629277(2-(4-fluorophenyl)-N-(4-{7-[methyl(1-methylpiperid...)
Affinity DataIC50: 32.9nMAssay Description:Recombinant fusion protein of N-terminal Glutathion-S-Transferase (GST) and full-length human CSNK1A1, expressed by baculovirus infected insect cells...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
Go to US Patent

TargetEpidermal growth factor receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM629277(2-(4-fluorophenyl)-N-(4-{7-[methyl(1-methylpiperid...)
Affinity DataIC50: 1.09E+3nMAssay Description:For the assay 50 nl of a 100 fold concentrated solution of the test compound in DMSO was pipetted into either a black low volume 384 well microtiter ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
Go to US Patent