BDBM629256 2-(4-fluorophenyl)-N-[4-(7-phenyl-5H-pyrrolo[2,3-b]pyrazin-6-yl)pyridin-2-yl]acetamide::US20230339939, Example 18

SMILES Fc1ccc(CC(=O)Nc2cc(ccn2)-c2[nH]c3nccnc3c2-c2ccccc2)cc1

InChI Key InChIKey=GYGWAOFCLMDYCF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 629256   

TargetCasein kinase I isoform alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM629256(2-(4-fluorophenyl)-N-[4-(7-phenyl-5H-pyrrolo[2,3-b...)
Affinity DataIC50: 3.33nMAssay Description:Recombinant fusion protein of N-terminal Glutathion-S-Transferase (GST) and full-length human CSNK1A1, expressed by baculovirus infected insect cells...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
Go to US Patent

TargetCasein kinase I isoform alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM629256(2-(4-fluorophenyl)-N-[4-(7-phenyl-5H-pyrrolo[2,3-b...)
Affinity DataIC50: 260nMAssay Description:Recombinant fusion protein of N-terminal Glutathion-S-Transferase (GST) and full-length human CSNK1A1, expressed by baculovirus infected insect cells...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
Go to US Patent

TargetEpidermal growth factor receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM629256(2-(4-fluorophenyl)-N-[4-(7-phenyl-5H-pyrrolo[2,3-b...)
Affinity DataIC50: 2.00E+4nMAssay Description:For the assay 50 nl of a 100 fold concentrated solution of the test compound in DMSO was pipetted into either a black low volume 384 well microtiter ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
Go to US Patent