BDBM629248 2-(4-fluorophenyl)-N-[4-(6-fluoro-3-phenyl-1H-pyrrolo[3,2-b]pyridin-2-yl)pyridin-2-yl]acetamide::US20230339939, Example 10

SMILES Fc1ccc(CC(=O)Nc2cc(ccn2)-c2[nH]c3cc(F)cnc3c2-c2ccccc2)cc1

InChI Key InChIKey=ZPGJWXXQFLAVAY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 629248   

TargetCasein kinase I isoform alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM629248(2-(4-fluorophenyl)-N-[4-(6-fluoro-3-phenyl-1H-pyrr...)
Affinity DataIC50: 3.83nMAssay Description:Recombinant fusion protein of N-terminal Glutathion-S-Transferase (GST) and full-length human CSNK1A1, expressed by baculovirus infected insect cells...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
Go to US Patent

TargetCasein kinase I isoform delta(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM629248(2-(4-fluorophenyl)-N-[4-(6-fluoro-3-phenyl-1H-pyrr...)
Affinity DataIC50: 4.27nMAssay Description:Recombinant fusion protein of N-terminal Glutathion-S-Transferase (GST) and full-length human CSNK1D, expressed by baculovirus infected insect cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
Go to US Patent

TargetCasein kinase I isoform alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM629248(2-(4-fluorophenyl)-N-[4-(6-fluoro-3-phenyl-1H-pyrr...)
Affinity DataIC50: 302nMAssay Description:Recombinant fusion protein of N-terminal Glutathion-S-Transferase (GST) and full-length human CSNK1A1, expressed by baculovirus infected insect cells...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
Go to US Patent

TargetEpidermal growth factor receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM629248(2-(4-fluorophenyl)-N-[4-(6-fluoro-3-phenyl-1H-pyrr...)
Affinity DataIC50: 2.00E+4nMAssay Description:For the assay 50 nl of a 100 fold concentrated solution of the test compound in DMSO was pipetted into either a black low volume 384 well microtiter ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
Go to US Patent