BDBM629236 1-(4-fluoro-3-methyl-phenyl)-2-isopropyl-3-[3-(2H-tetrazol-5-yl)cyclobutyl]indol-5-ol (217)::US20230339915, Compound 217

SMILES CC(C)c1c([C@@H]2C[C@@H](C2)c2nn[nH]n2)c2cc(O)ccc2n1-c1ccc(F)c(C)c1

InChI Key InChIKey=WDCSANPGBMYKFG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 629236   

TargetAlpha-1-antitrypsin(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM629236(US20230339915, Compound 217 | 1-(4-fluoro-3-methyl...)
Affinity DataIC50: 5.00E+3nMAssay Description:Assay Protocol: Pre-Incubation of Z-AAT with Compounds1. 7.5 μL of Z-AAT (20 nM) was incubated with compounds 1-227 in a GCA plate for 1 hour at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
Go to US Patent