BDBM629235 N-((3-(1-(4-fluoro-3-methylphenyl)-5-hydroxy-2-isopropyl-1H-indol-3-yl)azetidin-1-yl)sulfonyl)acetamide (216)::US20230339915, Compound 216

SMILES CC(C)c1c([C@@H]2COC[C@@H]2C#N)c2cc(O)ccc2n1-c1ccc(F)c(C)c1

InChI Key InChIKey=XYINOADJOIZNAV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 629235   

TargetAlpha-1-antitrypsin(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM629235(US20230339915, Compound 216 | N-((3-(1-(4-fluoro-3...)
Affinity DataIC50: 5.00E+3nMAssay Description:Assay Protocol: Pre-Incubation of Z-AAT with Compounds1. 7.5 μL of Z-AAT (20 nM) was incubated with compounds 1-227 in a GCA plate for 1 hour at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
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