BDBM629142 4-[3-(5-Fluoro-2-pyridyl)-1-methyl-pyrazol-4-yl]-1H-pyrrolo[2,3-b]pyridin-::US20230339900, Example 119

SMILES Cn1cc(c(n1)-c1ccc(F)cn1)-c1cc(N)nc2[nH]ccc12

InChI Key InChIKey=RLZXBOYSNLUDLM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 629142   

TargetCasein kinase I isoform delta(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM629142(US20230339900, Example 119 | 4-[3-(5-Fluoro-2-pyri...)
Affinity DataIC50: 32nMAssay Description:In this assay, CSNK1D phosphorylates a substrate peptide PLSRTL-pS-VASLPGL in the presence of ATP. This substrate peptide has been modeled after the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
Go to US Patent

TargetCasein kinase I isoform delta(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM629142(US20230339900, Example 119 | 4-[3-(5-Fluoro-2-pyri...)
Affinity DataIC50: 32nMAssay Description:Displacement of kinase tracer 8 from NanoLuc-tagged CK1 delta (unknown origin) transfected in CHO cells by BRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 14(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM629142(US20230339900, Example 119 | 4-[3-(5-Fluoro-2-pyri...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of p38 alpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed