BDBM629108 4-(3-(5-Fluoropyridin-2-yl)-1-methyl-1H-pyrazol-4-yl)-2-(trifluoromethyl)-::US20230339900, Example 85

SMILES Cn1cc(c(n1)-c1ccc(F)cn1)-c1ccnc2[nH]c(cc12)C(F)(F)F

InChI Key InChIKey=OMEJGENWYHYKFW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 629108   

TargetCasein kinase I isoform delta(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM629108(US20230339900, Example 85 | 4-(3-(5-Fluoropyridin-...)
Affinity DataIC50: 255nMAssay Description:In this assay, CSNK1D phosphorylates a substrate peptide PLSRTL-pS-VASLPGL in the presence of ATP. This substrate peptide has been modeled after the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
Go to US Patent

TargetCasein kinase I isoform delta(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM629108(US20230339900, Example 85 | 4-(3-(5-Fluoropyridin-...)
Affinity DataIC50: 250nMAssay Description:Displacement of kinase tracer 8 from NanoLuc-tagged CK1 delta (unknown origin) transfected in CHO cells by BRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 14(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM629108(US20230339900, Example 85 | 4-(3-(5-Fluoropyridin-...)
Affinity DataIC50: 200nMAssay Description:Inhibition of p38 alpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed