BDBM628887 US20230339896, Example 5

SMILES CN1CCc2cc(F)c(Nc3ncc(Cl)c(n3)N3C[C@@](C)(CC(O)=O)c4ccccc34)cc2C1

InChI Key InChIKey=WPXJRLVVPUHMFQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 628887   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Qilu Regor Therapeutics

US Patent
LigandPNGBDBM628887(US20230339896, Example 5)
Affinity DataIC50: 0.200nMAssay Description:The ADP-GLO Kinase Assay (Promega Corp., Madison, WI) measures ADP formed from a kinase reaction. According to the manufacture, the ADP formed in a k...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
Go to US Patent