BDBM628883 US20230339896, Example 1

SMILES COc1cc2CCN(C)Cc2cc1Nc1ncc(Cl)c(n1)N1CC(C)(CC(O)=O)c2ccccc12

InChI Key InChIKey=ACDOKDDKCMNUIJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 628883   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Qilu Regor Therapeutics

US Patent
LigandPNGBDBM628883(US20230339896, Example 1)
Affinity DataIC50: 0.5nMAssay Description:The ADP-GLO Kinase Assay (Promega Corp., Madison, WI) measures ADP formed from a kinase reaction. According to the manufacture, the ADP formed in a k...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
Go to US Patent