BDBM62811 2-(4-methylphenyl)-3-oxidanyl-chromen-4-one::3-hydroxy-2-(4-methylphenyl)-1-benzopyran-4-one::3-hydroxy-2-(4-methylphenyl)chromen-4-one::3-hydroxy-2-(p-tolyl)chromone::MLS000114653::SMR000092000::cid_265711

SMILES Cc1ccc(cc1)-c1oc2ccccc2c(=O)c1O

InChI Key InChIKey=QAHZLNKOVIYDGB-UHFFFAOYSA-N

Data  3 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 62811   

TargetHeat shock factor protein 1(Mouse)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM62811(MLS000114653 | 2-(4-methylphenyl)-3-oxidanyl-chrom...)
Affinity DataEC50: >1.95E+5nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2011
Entry Details
PCBioAssay
TargetGlycogen synthase kinase-3 beta(Human)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM62811(MLS000114653 | 2-(4-methylphenyl)-3-oxidanyl-chrom...)
Affinity DataEC50: >3.00E+5nMAssay Description:Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2011
Entry Details
PCBioAssay
TargetImportin subunit alpha-1(Human)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM62811(MLS000114653 | 2-(4-methylphenyl)-3-oxidanyl-chrom...)
Affinity DataEC50:  1.68E+4nMAssay Description:Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2011
Entry Details
PCBioAssay
TargetRecBCD enzyme subunit RecD(Escherichia coli (strain K12))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM62811(MLS000114653 | 2-(4-methylphenyl)-3-oxidanyl-chrom...)
Affinity DataIC50: 1.19E+5nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2011
Entry Details
PCBioAssay
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM62811(MLS000114653 | 2-(4-methylphenyl)-3-oxidanyl-chrom...)
Affinity DataIC50: 2.09E+4nMAssay Description:Inhibition of wild type recombinant human RET using peptide as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM62811(MLS000114653 | 2-(4-methylphenyl)-3-oxidanyl-chrom...)
Affinity DataIC50: 2.16E+4nMAssay Description:Inhibition of recombinant human VEGFR2 using peptide as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed