BDBM627422 (S,E)-1-(2-((5-Iodopyridin-3-yl)methoxy)-4-(2-(2-methyl-[1,1'-biphenyl]-3-yl)vinyl)-5-(trifluoromethyl)benzyl)piperidine-2-carboxylic acid::US20230331675, Compound 82

SMILES Cc1c(\C=C\c2cc(OCc3cncc(I)c3)c(CN3CCCC[C@H]3C(O)=O)cc2C(F)(F)F)cccc1-c1ccccc1

InChI Key InChIKey=DVFPFOJQIFIMIZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 627422   

TargetProgrammed cell death 1 ligand/protein 1(Human)
Guangzhou Maxinovel Pharmaceuticals

US Patent
LigandPNGBDBM627422((S,E)-1-(2-((5-Iodopyridin-3-yl)methoxy)-4-(2-(2-m...)
Affinity DataIC50: 1.85nMAssay Description:Homogeneous time-resolved fluorescence (HTRF) binding assay was used to determine the binding ability of the compound of the present disclosure to PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2023
Entry Details
Go to US Patent