BDBM627391 (S,E)-1-(5-Chloro-2-methoxy-4-(2-(2-methyl-[1,1'-biphenyl]-3-yl)vinyl)benzyl)piperidine-2-carboxylic acid::US20230331675, Compound 58::US20230331675, Compound 59

SMILES COc1cc(\C=C\c2cccc(c2C)-c2ccccc2)c(Cl)cc1CN1CCCC[C@H]1C(O)=O

InChI Key InChIKey=LEKIWXXXRQSDSA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 627391   

TargetProgrammed cell death 1 ligand/protein 1(Human)
Guangzhou Maxinovel Pharmaceuticals

US Patent
LigandPNGBDBM627391(US20230331675, Compound 58 | US20230331675, Compou...)
Affinity DataIC50: 6.80nMAssay Description:Homogeneous time-resolved fluorescence (HTRF) binding assay was used to determine the binding ability of the compound of the present disclosure to PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2023
Entry Details
Go to US Patent

TargetProgrammed cell death 1 ligand/protein 1(Human)
Guangzhou Maxinovel Pharmaceuticals

US Patent
LigandPNGBDBM627391(US20230331675, Compound 58 | US20230331675, Compou...)
Affinity DataIC50: 8.90nMAssay Description:Homogeneous time-resolved fluorescence (HTRF) binding assay was used to determine the binding ability of the compound of the present disclosure to PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2023
Entry Details
Go to US Patent