BDBM627355 (S,E)-4-(4-(2-(2-Cyano-[1,1'-biphenyl]-3-yl)vinyl)-2,5-dimethylbenzyl)morpholine-3-carboxylic acid::US20230331675, Compound 11

SMILES Cc1cc(\C=C\c2cccc(-c3ccccc3)c2C#N)c(C)cc1CN1CCOC[C@H]1C(O)=O

InChI Key InChIKey=NPXCQIPIFSRQKL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 627355   

TargetProgrammed cell death 1 ligand/protein 1(Human)
Guangzhou Maxinovel Pharmaceuticals

US Patent
LigandPNGBDBM627355((S,E)-4-(4-(2-(2-Cyano-[1,1'-biphenyl]-3-yl)vinyl)...)
Affinity DataIC50: 10.1nMAssay Description:Homogeneous time-resolved fluorescence (HTRF) binding assay was used to determine the binding ability of the compound of the present disclosure to PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2023
Entry Details
Go to US Patent