BDBM627345 (S,E)-1-(4-(2-(2-Cyano-[1,1'-biphenyl]-3-yl)vinyl)-3-trifluoromethylbenzyl)piperidine-2-carboxylic acid::US20230331675, Compound 1

SMILES OC(=O)[C@@H]1CCCCN1Cc1ccc(\C=C\c2cccc(-c3ccccc3)c2C#N)c(c1)C(F)(F)F

InChI Key InChIKey=PAAUGUKJKPMTRF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 627345   

TargetProgrammed cell death 1 ligand/protein 1(Human)
Guangzhou Maxinovel Pharmaceuticals

US Patent
LigandPNGBDBM627345((S,E)-1-(4-(2-(2-Cyano-[1,1'-biphenyl]-3-yl)vinyl)...)
Affinity DataIC50: 10.2nMAssay Description:Homogeneous time-resolved fluorescence (HTRF) binding assay was used to determine the binding ability of the compound of the present disclosure to PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2023
Entry Details
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