BDBM627183 3-(3-(difluoromethoxy)phenyl)-7- fluoro-1-isopropyl-N-(3-methyl-1,1- dioxidothietan-3-yl)-1H-indazole-6- carboxamide::US11787810, Example 34

SMILES CC(C)n1nc(-c2cccc(OC(F)F)c2)c2ccc(C(=O)NC3(C)CS(=O)(=O)C3)c(F)c12

InChI Key InChIKey=OACPVTGQUHYNOR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 627183   

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM627183(3-(3-(difluoromethoxy)phenyl)-7- fluoro-1-isopropy...)
Affinity DataIC50: 5.20nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13C18-triolein (13C-1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
US Patent