BDBM626244 1,1′-(((((2,2′-dimethyl-[1,1′-biphenyl]-3,3′-diyl) bis (methylene)) bis (oxo))bis (2-methoxypyridine-6,3-diyl)) bis (methylene)) bis (piperidine-2-carboxylic acid) ::US11787766, Compound 9

SMILES COc1nc(OCc2cccc(c2C)-c2cccc(COc3ccc(CN4CCCCC4C(O)=O)c(OC)n3)c2C)ccc1CN1CCCCC1C(O)=O

InChI Key InChIKey=AJNAOGGNVADJOV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 626244   

TargetProgrammed cell death 1 ligand/protein 1(Human)
Shanghai Ennovabio Pharmaceuticals

US Patent
LigandPNGBDBM626244(US11787766, Compound 9 | 1,1′-(((((2,2′...)
Affinity DataIC50: 10nMAssay Description:PD1/PD-L1 binding assay kit (Cisbio, Cat #63ADK000CPDEC) was used, which includes two proteins, Tag 1-PD-L1 and Tag 2-PD-1, and two antibodies, Anti-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
Go to US Patent