BDBM625454 US20230322789, Compound 87::US20230322789, Example 54

SMILES CN1C[C@@H]2C[C@H]1CN2c1ccc(cc1)-c1n[nH]c2cc(=O)n(nc12)-c1c(C)cccc1C

InChI Key InChIKey=VXQHJOCPEKZJIT-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 625454   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Broadenbio

US Patent

LigandBDBM625454(US20230322789, Compound 87 | US20230322789, Exampl...)Copy SMILESCopy InChI

Affinity DataIC50: 50nMAssay Description:1. HPK1 Kinase Activity Inhibition Test. The kinase activity of HPK1 is manifested as activity of autophosphorylation and phosphorylation of downstre...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
11/22/2023
Entry Details
Copy Entry DOIGo to US Patent

Copy Rxn URL