BDBM625427 US20230322789, Compound 27::US20230322789, Example 27

SMILES COc1cccc(F)c1-n1nc2c(n[nH]c2cc1=O)-c1ccc(nc1)N1CCOCC1

InChI Key InChIKey=YEXRPVHFTWESKG-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 625427   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Broadenbio

US Patent

LigandBDBM625427(US20230322789, Compound 27 | US20230322789, Exampl...)Copy SMILESCopy InChI

Affinity DataIC50: 50nMAssay Description:1. HPK1 Kinase Activity Inhibition Test. The kinase activity of HPK1 is manifested as activity of autophosphorylation and phosphorylation of downstre...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
11/22/2023
Entry Details
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