BDBM625390 US20230322788, Compound A17

SMILES C[C@H]1CN(CCN1c1nc(OC[C@@H]2CCCN2C)nn2c(Cc3cccc4ccccc34)cnc12)C(=O)C=C

InChI Key InChIKey=CBKVUXGEXFGPMC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 625390   

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene

US Patent
LigandPNGBDBM625390(US20230322788, Compound A17)
Affinity DataIC50: 2.93E+3nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
Go to US Patent