BDBM625173 2-((4-(3-(4-Chloro-2-fluorophenyl)-2,3-dihydrobenzo[b][1,4]dioxan-5-yl)piperidin-1-yl)methyl)-3-((S)-oxetan-2-ylmethyl)-3H-imidazo[4,5-b]pyridine-5-carboxylic acid (A Mixture of Diastereomers) 12::US20230322756, Example 12

SMILES OC(=O)c1ccc2nc(CN3CCC(CC3)c3cccc4OCC(Oc34)c3ccc(Cl)cc3F)n(C[C@@H]3CCO3)c2n1

InChI Key InChIKey=PRVFCVMDILYQNK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 625173   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM625173(US20230322756, Example 12 | 2-((4-(3-(4-Chloro-2-f...)
Affinity DataIC50: 2.61E+4nMAssay Description:In this experiment, a manual patch-clamp system (HEKA EPC-10 signal amplifier and digital conversion system, purchased from HEKA Electronics, Germany...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
Go to US Patent