BDBM625172 2-(((S)-4-((S)-3-(4-Chloro-2-fluorophenyl)-2,3-dihydrobenzo[b][1,4]dioxan-5-yl)-2-methylpiperazin-1-yl)methyl)-1-(((S)-oxetan-2-yl)methyl)-1H-benzo[d]imidazole-6-carboxylic acid 6::US20230322756, Example 6

SMILES OC(=O)c1ccc2nc3CN4CCN(C[C@@H]4C([C@@H]4CCO4)n3c2c1)c1cccc2OC[C@@H](Oc12)c1ccc(Cl)cc1F

InChI Key InChIKey=NVCFHVCBWVPVJC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 625172   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM625172(US20230322756, Example 6 | 2-(((S)-4-((S)-3-(4-Chl...)
Affinity DataIC50: 3.00E+4nMAssay Description:In this experiment, a manual patch-clamp system (HEKA EPC-10 signal amplifier and digital conversion system, purchased from HEKA Electronics, Germany...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
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