BDBM624862 US20230322721, Example 22

SMILES CCOc1ccc(nc1)-c1nnc([C@H]2C[C@@H](C2)NC(=O)c2cccc3c(ccnc23)N(C)C)n1-c1ccccc1F

InChI Key InChIKey=MGHZPYNCIXIKPJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 624862   

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Oslo Universitetssykehus

US Patent
LigandPNGBDBM624862(US20230322721, Example 22)
Affinity DataIC50: 2.10nMAssay Description:Each compound was dissolved in DMSO to a concentration of 10 mM and further diluted to 100 μM using acetonitrile. Liver microsomes from selected...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
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