BDBM624857 US20230322721, Example 4

SMILES CCOc1ccc(nc1)-c1nnc([C@H]2C[C@@H](C2)NC(=O)c2cccc3[n+]([O-])ccnc23)n1-c1ccccc1F

InChI Key InChIKey=FYFIJZXOLDTNNS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 624857   

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Oslo Universitetssykehus

US Patent
LigandPNGBDBM624857(US20230322721, Example 4)
Affinity DataIC50: 1.60nMAssay Description:Each compound was dissolved in DMSO to a concentration of 10 mM and further diluted to 100 μM using acetonitrile. Liver microsomes from selected...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
Go to US Patent