BDBM624822 US20230322706, Example 8

SMILES CCOc1ccccc1Oc1cncc(c1)-c1cncc(Nc2nccc(n2)N2CCC[C@H](C2)C(O)=O)n1

InChI Key InChIKey=YQJQKNWOGLGSGF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 624822   

TargetDiacylglycerol O-acyltransferase 2(Human)
LG Chem

US Patent
LigandPNGBDBM624822(US20230322706, Example 8 | US12459915, Example 8)
Affinity DataIC50: 1.80E+3nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2026
Entry Details US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
LG Chem

US Patent
LigandPNGBDBM624822(US20230322706, Example 8 | US12459915, Example 8)
Affinity DataIC50: 1.80E+3nMAssay Description:1. Preparation of DGAT2 Expression Vector. In order to prepare the pBacPAK9-DGAT2, which is DGAT2 expression vector, the human DGAT2 gene amplified b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent