BDBM624733 US11780851, Example 3::US11780851, Example 61

SMILES Cc1c2Nc3ncc4c(Cl)nn(CCCOc2nn1[C@@H]1CCCOC1)c4n3

InChI Key InChIKey=VVXMSLYSMGFSGG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 624733   

LigandPNGBDBM624733(US11780851, Example 61 | US11780851, Example 3)
Affinity DataIC50: 2.20nMAssay Description:The LRRK2 kinase was obtained from Invitrogen (Life Technologies Corporation) and comprises residue 970 to 2527 of the full length human wild-type LR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2023
Entry Details
US Patent

LigandPNGBDBM624733(US11780851, Example 61 | US11780851, Example 3)
Affinity DataIC50: 9.20nMAssay Description:The LRRK2 kinase was obtained from Invitrogen (Life Technologies Corporation) and comprises residue 970 to 2527 of the full length human wild-type LR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2023
Entry Details
US Patent

LigandPNGBDBM624733(US11780851, Example 61 | US11780851, Example 3)
Affinity DataIC50: 10nMAssay Description:The LRRK2 kinase was obtained from Invitrogen (Life Technologies Corporation) and comprises residue 970 to 2527 of the full length human wild-type LR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2023
Entry Details
US Patent

LigandPNGBDBM624733(US11780851, Example 61 | US11780851, Example 3)
Affinity DataIC50: 34nMAssay Description:The LRRK2 kinase was obtained from Invitrogen (Life Technologies Corporation) and comprises residue 970 to 2527 of the full length human wild-type LR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2023
Entry Details
US Patent