BDBM624506 8-methoxy-4-(4-(S- methylsulfonimidoyl)phenoxy)quinoline-3- carbonitrile::US11780849, Compound 58

SMILES COc1cccc2c(Oc3ccc(cc3)S(C)(=N)=O)c(cnc12)C#N

InChI Key InChIKey=HTUWXELJZGYUHJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 624506   

TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Human)
Volastra Therapeutics

US Patent
LigandPNGBDBM624506(8-methoxy-4-(4-(S- methylsulfonimidoyl)phenoxy)qui...)
Affinity DataIC50: 505nMAssay Description:Assay 1: Test compounds were plated in a 3 dilution scheme in a 384 well plate. To 50 nL of test compound in DMSO was added 2.5 μL ENPP-1 ECD in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2023
Entry Details
Go to US Patent

TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Human)
Volastra Therapeutics

US Patent
LigandPNGBDBM624506(8-methoxy-4-(4-(S- methylsulfonimidoyl)phenoxy)qui...)
Affinity DataIC50: 5.10E+4nMAssay Description:Assay 1: Test compounds were plated in a 3 dilution scheme in a 384 well plate. To 50 nL of test compound in DMSO was added 2.5 μL ENPP-1 ECD in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2023
Entry Details
Go to US Patent