BDBM622985 (13E,14E,34E)-17-(methylamino)- 31H-2,6-diaza-1(5,3)- pyrazolo[1,5-a]pyrimidina- 3(4,1)-pyrazolacycloheptaphan- 7-one::US11780842, Compound 47

SMILES CNc1cc2Nc3cnn(CCNC(=O)c4cnn1c4n2)c3

InChI Key InChIKey=PNYUARYSNBBYOX-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 622985   

TargetInterferon alpha-1/13/Tyrosine-protein kinase JAK1/Non-receptor tyrosine-protein kinase TYK2(Human)
Ventyx Biosciences

US Patent

LigandBDBM622985(US11780842, Compound 47 | (13E,14E,34E)-17-(methyl...)Copy SMILESCopy InChI

Affinity DataIC50: 5.50E+3nMAssay Description:10 mM test compound stock or 1 mM control compound stock (tofocitinib, ruxolitinib or staurosporine) in DMSO was diluted to 0.4 mM in DMSO. A 3-fold ...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
11/17/2023
Entry Details
Copy Entry DOIGo to US Patent

Copy Rxn URL