BDBM622982 (13E,14E)-17-(methylamino)-2,7- diaza-1(5,3)-pyrazolo[1,5- a]pyrimidina-3(1,3)- benzenacyclooctaphane-4,8- dione::US11780842, Compound 44

SMILES CNc1cc2Nc3cccc(c3)C(=O)CCNC(=O)c3cnn1c3n2

InChI Key InChIKey=YVHXLRVTJBXVRQ-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 622982   

TargetInterferon alpha-1/13/Tyrosine-protein kinase JAK1/Non-receptor tyrosine-protein kinase TYK2(Human)
Ventyx Biosciences

US Patent

LigandBDBM622982(US11780842, Compound 44 | (13E,14E)-17-(methylamin...)Copy SMILESCopy InChI

Affinity DataIC50: 5.50E+3nMAssay Description:10 mM test compound stock or 1 mM control compound stock (tofocitinib, ruxolitinib or staurosporine) in DMSO was diluted to 0.4 mM in DMSO. A 3-fold ...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
11/17/2023
Entry Details
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