BDBM622981 (12Z,33E,34E)-37-(methylamino)- 2,5-diaza-1(2,4)-thiazola-3(5,3)- pyrazolo[1,5- a]pyrimidinacyclooctaphan-4- one::US11780842, Compound 43

SMILES CNc1cc2Nc3nc(CCCNC(=O)c4cnn1c4n2)cs3

InChI Key InChIKey=ROSDNDTZZGPZLI-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 622981   

TargetInterferon alpha-1/13/Tyrosine-protein kinase JAK1/Non-receptor tyrosine-protein kinase TYK2(Human)
Ventyx Biosciences

US Patent

LigandBDBM622981(US11780842, Compound 43 | (12Z,33E,34E)-37-(methyl...)Copy SMILESCopy InChI

Affinity DataIC50: 5.50E+3nMAssay Description:10 mM test compound stock or 1 mM control compound stock (tofocitinib, ruxolitinib or staurosporine) in DMSO was diluted to 0.4 mM in DMSO. A 3-fold ...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
11/17/2023
Entry Details
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