BDBM622958 (13E,14E)-17-(methylamino)-4- oxa-2,7-diaza-1(5,3)- pyrazolo[1,5-a]pyrimidina- 3(1,2)-benzenacyclooctaphan-8- one::US11780842, Compound 20

SMILES CNc1cc2Nc3ccccc3OCCNC(=O)c3cnn1c3n2

InChI Key InChIKey=WITVLYHLGOZBMX-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 622958   

TargetInterferon alpha-1/13/Tyrosine-protein kinase JAK1/Non-receptor tyrosine-protein kinase TYK2(Human)
Ventyx Biosciences

US Patent

LigandBDBM622958(US11780842, Compound 20 | (13E,14E)-17-(methylamin...)Copy SMILESCopy InChI

Affinity DataIC50: 550nMAssay Description:10 mM test compound stock or 1 mM control compound stock (tofocitinib, ruxolitinib or staurosporine) in DMSO was diluted to 0.4 mM in DMSO. A 3-fold ...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
11/17/2023
Entry Details
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