BDBM622956 (13E,14E)-17-(methylamino)-2,7- diaza-1(5,3)-pyrazolo[1,5- a]pyrimidina-3(1,3)- benzenacyclooctaphan-8-one::US11780842, Compound 18::US11780842, Compound 24

SMILES CNc1cc2Nc3cccc(CCCNC(=O)c4cnn1c4n2)c3

InChI Key InChIKey=TWNQXFDQQVYTQB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 622956   

LigandPNGBDBM622956(US11780842, Compound 24 | (13E,14E)-17-(methylamin...)
Affinity DataIC50: 550nMAssay Description:10 mM test compound stock or 1 mM control compound stock (tofocitinib, ruxolitinib or staurosporine) in DMSO was diluted to 0.4 mM in DMSO. A 3-fold ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2023
Entry Details
Go to US Patent

LigandPNGBDBM622956(US11780842, Compound 24 | (13E,14E)-17-(methylamin...)
Affinity DataIC50: 550nMAssay Description:10 mM test compound stock or 1 mM control compound stock (tofocitinib, ruxolitinib or staurosporine) in DMSO was diluted to 0.4 mM in DMSO. A 3-fold ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2023
Entry Details
Go to US Patent