BDBM622949 (13E,14E)-17-(methylamino)-4-oxa-2,7-diaza-1(5,3)-pyrazolo[1,5-a]pyrimidina-3(1,3)-benzenacyclooctaphan-8-one::US11780842, Compound 14::US11780842, Compound 15::US11780842, Compound 7

SMILES CNc1cc2Nc3cccc(OCCNC(=O)c4cnn1c4n2)c3

InChI Key InChIKey=LJPDATKYTRMKSZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 622949   

LigandPNGBDBM622949((13E,14E)-17-(methylamino)-4-oxa-2,7-diaza-1(5,3)-...)
Affinity DataIC50: 500nMAssay Description:10 mM test compound stock or 1 mM control compound stock (tofocitinib, ruxolitinib or staurosporine) in DMSO was diluted to 0.4 mM in DMSO. A 3-fold ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2023
Entry Details
Go to US Patent

LigandPNGBDBM622949((13E,14E)-17-(methylamino)-4-oxa-2,7-diaza-1(5,3)-...)
Affinity DataIC50: 500nMAssay Description:10 mM test compound stock or 1 mM control compound stock (tofocitinib, ruxolitinib or staurosporine) in DMSO was diluted to 0.4 mM in DMSO. A 3-fold ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2023
Entry Details
Go to US Patent

LigandPNGBDBM622949((13E,14E)-17-(methylamino)-4-oxa-2,7-diaza-1(5,3)-...)
Affinity DataIC50: 500nMAssay Description:10 mM test compound stock or 1 mM control compound stock (tofocitinib, ruxolitinib or staurosporine) in DMSO was diluted to 0.4 mM in DMSO. A 3-fold ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2023
Entry Details
Go to US Patent