BDBM622601 US20230312601, Example 32

SMILES CO[C@H](C(F)F)c1c(Nc2ccc(cc2)[C@H](N(C)C(=O)C2CCN(CC2)C(=O)CO)C(F)(F)F)cnc2sc(C)nc12

InChI Key InChIKey=XGDRQFRJLRAQBF-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 622601   

LigandPNGBDBM622601(US20230312601, Example 32)
Affinity DataEC50:  113nMAssay Description:A Quenched Fluorescence Resonance Energy Transfer (Quench-FRET) enzyme assay was used to test the ability of exemplary MALT-1 inhibitors Example 1 to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
Go to US Patent