BDBM622581 US20230312601, Example 12

SMILES CO[C@H](C)c1c(Nc2ccc(cc2)[C@@H](C(F)F)N(C)C(=O)C2CCS(=O)(=O)CC2)cnc2sc(C)nc12

InChI Key InChIKey=KRRMPWOUOGBQSJ-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 622581   

LigandPNGBDBM622581(US20230312601, Example 12)
Affinity DataEC50:  61nMAssay Description:A Quenched Fluorescence Resonance Energy Transfer (Quench-FRET) enzyme assay was used to test the ability of exemplary MALT-1 inhibitors Example 1 to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
Go to US Patent

LigandPNGBDBM622581(US20230312601, Example 12)
Affinity DataEC50:  61nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed