BDBM622576 US20230312601, Example 7

SMILES CCN([C@@H](c1ccc(Nc2cnc3sc(C)nc3c2[C@H](C)OC)cc1)C(F)(F)F)C(=O)C1CCS(=O)(=O)CC1

InChI Key InChIKey=ZKSQPVHKXFBHOQ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 622576   

LigandPNGBDBM622576(US20230312601, Example 7)
Affinity DataEC50:  135nMAssay Description:A Quenched Fluorescence Resonance Energy Transfer (Quench-FRET) enzyme assay was used to test the ability of exemplary MALT-1 inhibitors Example 1 to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
Go to US Patent