BDBM622547 (7S)-5-ethyl-8-isopropyl-7-methyl-2-(((1-(3,4,5-trifluorobenzyl)-1H-pyrazol-4-yl)methyl)amino)-7,8-dihydropteridin-6(5H)-one::US20230312587, Compound 51

SMILES CCN1C(=O)[C@H](C)N(C(C)C)c2nc(NCc3cnn(Cc4cc(F)c(F)c(F)c4)c3)ncc12

InChI Key InChIKey=UQFGPDOBSXZOBD-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 622547   

TargetSerine/threonine-protein kinase PLK1(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM622547(US20230312587, Compound 51 | (7S)-5-ethyl-8-isopro...)
Affinity DataKi: >4.00E+3nMAssay Description:Compounds were screened for their ability to inhibit Plk1 using a radioactive-phosphate incorporation assay. Assays were carried out in a mixture of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
Go to US Patent