BDBM622424 US20230312576, Compound 81

SMILES O=C(Nc1cccc(c1)-n1cccc1)N1CCC(=CC1)c1ncnc2[nH]cc(C3CC3)c12

InChI Key InChIKey=RYYHCXZWRDDPPO-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 622424   

TargetLIM domain kinase 2(Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM622424(US20230312576, Compound 81)
Affinity DataKi:  9.98nMAssay Description:Inhibition of LIMK1 and LIMK2. Inhibition of LIMK1 and LIMK2 was measured with Lanthascreen Eu binding assay (Life Technologies). This TR-FRET assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
Go to US Patent

TargetLIM domain kinase 2(Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM622424(US20230312576, Compound 81)
Affinity DataKi:  10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetLIM domain kinase 1(Human)
University of Orleans

Curated by ChEMBL
LigandPNGBDBM622424(US20230312576, Compound 81)
Affinity DataKi:  13nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetLIM domain kinase 1(Human)
University of Orleans

Curated by ChEMBL
LigandPNGBDBM622424(US20230312576, Compound 81)
Affinity DataKi:  13.3nMAssay Description:Inhibition of LIMK1 and LIMK2. Inhibition of LIMK1 and LIMK2 was measured with Lanthascreen Eu binding assay (Life Technologies). This TR-FRET assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
Go to US Patent