BDBM622414 US20230312576, Compound 66

SMILES CC1CC(=CC(C)N1C(=O)Nc1cccc(OC(=O)N(C)C)c1)c1ncnc2[nH]cc(C)c12

InChI Key InChIKey=CNMVVVADKFPJMA-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 622414   

TargetLIM domain kinase 2(Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM622414(US20230312576, Compound 66)
Affinity DataKi:  8.49nMAssay Description:Inhibition of LIMK1 and LIMK2. Inhibition of LIMK1 and LIMK2 was measured with Lanthascreen Eu binding assay (Life Technologies). This TR-FRET assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
Go to US Patent

TargetLIM domain kinase 1(Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM622414(US20230312576, Compound 66)
Affinity DataKi:  58nMAssay Description:Inhibition of LIMK1 and LIMK2. Inhibition of LIMK1 and LIMK2 was measured with Lanthascreen Eu binding assay (Life Technologies). This TR-FRET assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
Go to US Patent