BDBM622399 US20230312576, Compound 31

SMILES COc1ccc(cc1)-c1cccc(NC(=O)N2CCC(=CC2)c2ncnc3[nH]cc(C)c23)c1

InChI Key InChIKey=FDJOHHPXPWKDPJ-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 622399   

TargetLIM domain kinase 1(Human)
University of Orleans

Curated by ChEMBL
LigandPNGBDBM622399(US20230312576, Compound 31)
Affinity DataKi:  12nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetLIM domain kinase 1(Human)
University of Orleans

Curated by ChEMBL
LigandPNGBDBM622399(US20230312576, Compound 31)
Affinity DataKi:  12.4nMAssay Description:Inhibition of LIMK1 and LIMK2. Inhibition of LIMK1 and LIMK2 was measured with Lanthascreen Eu binding assay (Life Technologies). This TR-FRET assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
Go to US Patent

TargetLIM domain kinase 2(Human)
University of Orleans

Curated by ChEMBL
LigandPNGBDBM622399(US20230312576, Compound 31)
Affinity DataKi:  25nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetLIM domain kinase 2(Human)
University of Orleans

Curated by ChEMBL
LigandPNGBDBM622399(US20230312576, Compound 31)
Affinity DataKi:  25.1nMAssay Description:Inhibition of LIMK1 and LIMK2. Inhibition of LIMK1 and LIMK2 was measured with Lanthascreen Eu binding assay (Life Technologies). This TR-FRET assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
Go to US Patent