BDBM621893 (S)-N-((R or S)-1-(3- chloro-2,4- difluorophenyl)-2- cyclohexylethyl)-2- oxoimidazolidine-4- carboxamide::US20230312528, Example 54A

SMILES Fc1ccc([C@H](CC2CCCCC2)NC(=O)[C@@H]2CNC(=O)N2)c(F)c1Cl

InChI Key InChIKey=KELXLBAQFIYSIK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 621893   

TargetSodium channel protein type 8 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM621893(US20230312528, Example 54A | (S)-N-((R or S)-1-(3-...)
Affinity DataIC50: 3.20nMAssay Description:Compounds were tested on human NaV1.8 and NaV1.5 channels stably expressed in human embryo kidney (HEK) 293 cells. Sodium current measurements on Qub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
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