BDBM621825 (S)-N-((R or S)-(4- chloropehnyl)(4- fluoro-3-(trifluoro- methyl)phenyl)methyl)- 2-oxoimidazolidine-4- carboxamide::US20230312528, Example 17B

SMILES Fc1ccc(cc1C(F)(F)F)[C@@H](NC(=O)[C@H]1CNC(=O)N1)c1ccc(Cl)cc1

InChI Key InChIKey=OKUOBJLNMMZBMG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 621825   

TargetSodium channel protein type 8 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM621825(US20230312528, Example 17B | (S)-N-((R or S)-(4- c...)
Affinity DataIC50: 7nMAssay Description:Compounds were tested on human NaV1.8 and NaV1.5 channels stably expressed in human embryo kidney (HEK) 293 cells. Sodium current measurements on Qub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
Go to US Patent