BDBM621816 (4S)-N-[((R or S)-5- chloro-6-cyclo- propylpyridin-3-yl)(3- chloro-2,4-difluoro- phenyl)methyl]-2- oxoimidazolidine-4- carboxamide::US20230312528, Example 13A

SMILES Fc1ccc([C@@H](NC(=O)[C@@H]2CNC(=O)N2)c2cnc(C3CC3)c(Cl)c2)c(F)c1Cl

InChI Key InChIKey=BSGRKUFRCCPBFO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 621816   

TargetSodium channel protein type 8 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM621816(US20230312528, Example 13A | (4S)-N-[((R or S)-5- ...)
Affinity DataIC50: 1.10nMAssay Description:Compounds were tested on human NaV1.8 and NaV1.5 channels stably expressed in human embryo kidney (HEK) 293 cells. Sodium current measurements on Qub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
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