BDBM621813 (4S)-N-{((R or S)-3- chloro-4-fluoro- phenyl)[5-fluoro-6- (2,2,2-trifluoro- ethoxy)pyridin-2- yl]methyl}-2- oxoimidazolidine-4- carboxamide::US20230312528, Example 11B

SMILES Fc1ccc(cc1Cl)[C@H](NC(=O)[C@H]1CNC(=O)N1)c1ccc(F)c(OCC(F)(F)F)n1

InChI Key InChIKey=IQKIYXKZUQZQIB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 621813   

TargetSodium channel protein type 8 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM621813(US20230312528, Example 11B | (4S)-N-{((R or S)-3- ...)
Affinity DataIC50: 3.90nMAssay Description:Compounds were tested on human NaV1.8 and NaV1.5 channels stably expressed in human embryo kidney (HEK) 293 cells. Sodium current measurements on Qub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
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