BDBM621712 (2S,4R)-1-[(2S)-2-[8-([[2,6-dimethoxy-4-(2-methyl-1-oxo-2,7-naphthyridin-4-yl)phenyl]methyl](methyl)amino)octanamido]-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide ::US11773085, Compound D19

SMILES COc1cc(cc(OC)c1CN(C)CCCCCCCC(=O)N[C@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(cc1)-c1scnc1C)C(C)(C)C)-c1cn(C)c(=O)c2cnccc12

InChI Key InChIKey=GPRXJUSJBGXJHA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 621712   

TargetBromodomain-containing protein 9 [133-239](Human)
Foghorn Therapeutics

US Patent
LigandPNGBDBM621712((2S,4R)-1-[(2S)-2-[8-([[2,6-dimethoxy-4-(2-methyl-...)
Affinity DataIC50: 55nMAssay Description:A mixture of biotinylated-ligand and SureLight Allophycocyanin-Streptavidin (APC-SA, PerkinElmer AD0201) in 50 mM HEPES (pH 7.4), 50 mM NaCl, 1 mM TC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2023
Entry Details
Go to US Patent