BDBM621690 4-(4-((dimethylamino)methyl)-3,5-dimethoxyphenyl)-6-(1H-imidazo[4,5-c]pyridin-2-yl)-2-methylisoquinolin-1(2H)-one ::US11773085, Compound B65

SMILES COc1cc(cc(OC)c1CN(C)C)-c1cn(C)c(=O)c2ccc(cc12)-c1nc2cnccc2[nH]1

InChI Key InChIKey=UUFOJUWVFZEMJS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 621690   

TargetBromodomain-containing protein 9 [133-239](Human)
Foghorn Therapeutics

US Patent
LigandPNGBDBM621690(4-(4-((dimethylamino)methyl)-3,5-dimethoxyphenyl)-...)
Affinity DataIC50: 55nMAssay Description:A mixture of biotinylated-ligand and SureLight Allophycocyanin-Streptavidin (APC-SA, PerkinElmer AD0201) in 50 mM HEPES (pH 7.4), 50 mM NaCl, 1 mM TC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2023
Entry Details
Go to US Patent