BDBM621680 4-[3,5-dimethoxy-4-[(methylamino)methyl]phenyl]-2-methyl-1,2-dihydro-2,7-naphthyridin-1-one ::US11773085, Compound B53

SMILES CNCc1c(OC)cc(cc1OC)-c1cn(C)c(=O)c2cnccc12

InChI Key InChIKey=OKHISWVFOXDTHL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 621680   

TargetBromodomain-containing protein 9 [133-239](Human)
Foghorn Therapeutics

US Patent
LigandPNGBDBM621680(4-[3,5-dimethoxy-4-[(methylamino)methyl]phenyl]-2-...)
Affinity DataIC50: 55nMAssay Description:A mixture of biotinylated-ligand and SureLight Allophycocyanin-Streptavidin (APC-SA, PerkinElmer AD0201) in 50 mM HEPES (pH 7.4), 50 mM NaCl, 1 mM TC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2023
Entry Details
Go to US Patent