BDBM621314 US11773078, Example 66::US11773078, Example 67

SMILES CNC(=O)OCC1CCN(Cc2cc(Oc3ccc(nc3)N3CCN(C)CC3)nc(c2)-c2cc(Cl)cc(Cl)c2)CC1

InChI Key InChIKey=FLEMCNDRTFUUAK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 621314   

TargetFurin [108-574](Human)
Glaxosmithkline Intellectual Property Development

US Patent
LigandPNGBDBM621314(US11773078, Example 67 | US11773078, Example 66)
Affinity DataIC50: 1.58nMAssay Description:Reactions were performed in black 384-well polystyrene low volume plates (Greiner). Furin (108-574-Tev-Flag-His) enzyme was expressed and purified fr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2023
Entry Details
Go to US Patent

TargetFurin [108-574](Human)
Glaxosmithkline Intellectual Property Development

US Patent
LigandPNGBDBM621314(US11773078, Example 67 | US11773078, Example 66)
Affinity DataIC50: 0.0400nMAssay Description:Reactions were performed in black 384-well polystyrene low volume plates (Greiner). Furin (108-574-Tev-Flag-His) enzyme was expressed and purified fr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2023
Entry Details
Go to US Patent